Argentina vs. Chile: Prediction, Odds, Betting Tips and Best Bets for CONMEBOL World Cup Qualifying Clash

The CONMEBOL World Cup qualifiers are back this week, with Argentina set to face off against Chile at Estadio Monumental in Buenos Aires, promising an exciting match-up for fans.

The reigning world and South American champions are clear favourites to win with the oddsmakers and were victorious when these sides last met, Lautaro Martinez scoring a late winner in a 1-0 triumph in the Copa America group stage.

Lionel Scaloni's side sit comfortably top of the CONMEBOL standings, with five wins from their first six games putting them in a strong position to qualify for the 2026 World Cup in the United States, Mexico and Canada. Chile, meanwhile, are facing a battle to join them at the expanded finals, having taken only five points from six matches. Only Bolivia and Peru are below them in the 10-team standings.

BET NOW:Latest odds for 2026 World Cup qualifying and best bets for Argentina vs. Chile on BetMGM

The Sporting News looks at the latest odds and predictions for this fixture.

MORE: A complete guide to betting on soccer in the United States

Argentina vs. Chile prediction, oddsMoneyline lean: Argentina (-275)Score prediction: Argentina 2-0 Chile

Even without Lionel Messi, Argentina are logical favourites to win against a struggling Chilean side. With that in mind, it makes sense to add different selections to find more appealing odds.

Argentina to win to nil is priced at -105 with BetMGM, which is a better option than simply backing a home victory.

Similarly, there could be value in backing a low-scoring game: the Albiceleste have failed to score more than once in their past two home games against Chile in World Cup qualifying, and they didn't manage to do so in their most recent Copa America clash.

 BetMGM
(USA)Argentina win-275Draw+360Chile win+775Both teams
to scoreY: +130
N: -185Over / Under
2.5 goalsO: -115
U: -120Argentina
-1.5 goals+105Chile
+1.5 goals-145Argentina vs. Chile match factsDate: Thursday, Sept. 5, 2024Kickoff Time: 9:00 p.m. local (8:00 p.m. ET / 5:00 p.m. PT)Location: Estadio Mas Monumental (Buenos Aires, Argentina)Referee: TBCLast meeting: Argentina 1-0 Chile (Jun. 25, 2024 | Copa America)Argentina vs. Chile best betPick: Argentina to win and Chile not to scoreOdds: -105 (BetMGM)

Argentina only conceded one goal at the Copa America — in the 1-1 quarterfinal draw with Ecuador — and won each of their other six matches. Likewise, in World Cup qualifying, all five of their wins to date have come without allowing their opponents a goal.

Chile, meanwhile, have only scored three times in 2026 World Cup qualifiers and failed to find the net once at the Copa America. This feels like an easy selection.

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